How to Get Compound Semaglutide: Your Ultimate Guide

Compounded semaglutide can aid in weight loss and improve metabolic health. It’s sometimes used as an alternative to FDA-approved semaglutide products like Ozempic^® or Wegovy^®. Compounded versions have not undergone FDA approval, and their safety and effectiveness have not been established to the same degree. As interest grows, so does the need for reliable information on how to get compounded semaglutide safely and effectively.

This guide explains the process of obtaining compounded semaglutide with an emphasis on safety and medical supervision. Compounded medications come with potential risks, and it is necessary to work with a licensed healthcare provider and compounding pharmacy. This guide covers everything from understanding what compounded semaglutide is and how it works to exploring its benefits for weight loss. The guide also details where to get semaglutide from compounding pharmacies, how to choose a reputable provider, and the steps involved in getting a prescription. It also compares compounded semaglutide to other formulations, providing information that individuals can use to make an informed decision about a potential weight management plan.

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Key Takeaways

• Compounded semaglutide is a custom-made medication that may be used as an alternative to FDA-approved semaglutide products like Ozempic^{® [1]}.

• While compounded semaglutide can be helpful in certain situations, it has not undergone the same rigorous FDA approval process as Ozempic^® for safety and efficacy ^[1].

• To get compounded semaglutide safely:

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• Consult a healthcare provider for a prescription and guidance

• Choose a reputable, licensed compounding pharmacy

• Verify the pharmacy sources ingredients from FDA-registered facilities

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• When using semaglutide:

• Follow dosing instructions carefully, typically weekly injections

• Monitor blood sugar levels closely, especially when starting treatment

• Follow your doctor's meal plan and exercise recommendations

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• Work with an experienced healthcare team for proper dosing, monitoring, and lifestyle guidance to support your weight management goals safely and effectively ^[2].

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What is Compounded Semaglutide and How Does it Work?

Compounded semaglutide is a custom-made medication that contains the active ingredient semaglutide, which is found in FDA-approved medications like Ozempic^® and Wegovy^®. Semaglutide belongs to a class of drugs known as glucagon-like peptide-1 (GLP-1) receptor agonists ^[5]. It mimics the actions of naturally occurring GLP-1 hormones in the body, which play a crucial role in regulating blood sugar levels and appetite ^[5].

Compounded semaglutide is prepared by compounding pharmacies to meet specific patient needs, such as addressing allergies to certain ingredients or providing alternative formulations ^[4]. It's always essential to understand semaglutide dosages and guidelines. Follow your healthcare provider's instructions carefully and report any side effects or concerns you may experience while using semaglutide.

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How Semaglutide Works

Semaglutide primarily operates through three main mechanisms:

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1. Enhancing Insulin Release: It stimulates the pancreas to release insulin when blood sugar levels rise, thereby improving glucose control ^[5].

2. Appetite Suppression: Semaglutide acts on the brain's appetite centers, specifically targeting GLP-1 receptors. This induces a sensation of fullness and reduces the desire to overeat ^{[4] [5]}.

3. Slowing Gastric Emptying: It delays the emptying of food from the stomach, leading to prolonged feelings of satiety and reduced calorie intake ^{[4] [5]}.

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Compounded Semaglutide Formulations

Compounded semaglutide may be available in various dosage forms, including:

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• Injections

• Sublingual (under the tongue) drops

• Orally disintegrating tablets (ODTs)

• Oral capsules or tablets

• Nasal sprays

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It's important to note that compounded semaglutide medications are not FDA-approved, and their safety and effectiveness haven't been established to the same degree as commercial products. Some compounded versions may contain additional ingredients, such as vitamin B12, which haven't been tested with semaglutide.

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Benefits of Compounded Semaglutide for Weight Loss

Compounded semaglutide may offer an alternative during shortages of FDA-approved semaglutide products. Its safety and efficacy have not been established to the same standards. Patients should consult a healthcare provider to discuss the potential risks and benefits. This medication mimics the action of Glucagon-like peptide 1 (GLP-1), a hormone responsible for regulating blood sugar levels and managing hunger and fullness cues ^[6]. By targeting GLP-1 receptors in the brain, semaglutide helps control appetite, potentially leading to reduced food intake ^[4].

As with any other weight loss medication, there are pros and cons of semaglutide for weight loss. One of the primary benefits of compounded semaglutide is its effectiveness in promoting weight loss. Clinical trials have shown notable results, with participants losing an average of 15% of their body weight ^[7]. It’s been shown that this weight reduction can be maintained for over a year with continued use ^[4].

Compounded semaglutide also offers advantages in terms of cost and accessibility. It is available at a fraction of the cost of name-brand drugs, making it a more affordable option for many patients ^[4]. On average, compounded semaglutide costs less than $500 per month, considerably less than brand-name equivalents^[6].

Another benefit of compounded semaglutide is its potential to regulate blood sugar levels, which is particularly beneficial for individuals with type 2 diabetes ^[7]. This dual action of weight loss and blood sugar control makes it an attractive option for patients managing both conditions.

Compounded semaglutide also provides flexibility in treatment. It allows for individualization of dosage and can be combined with additional medications for increased efficiency ^[6]. This customization can help minimize side effects and optimize results for each patient.

Lastly, compounded semaglutide offers a non-invasive alternative to weight loss procedures like bariatric surgery ^[7]. This makes it an appealing option for individuals seeking effective weight management without the risks associated with surgical interventions.

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Where to Get Compounded Semaglutide: Compounding Pharmacies vs Online Providers

Individuals seeking compounded semaglutide have two primary options: traditional compounding pharmacies and online providers. Each option has its own considerations and potential risks.

To get approved for semaglutide, individuals must consult with a qualified healthcare professional who may prescribe them the medication. Individuals should also meet some minimum requirements, such as:

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1. To lose weight (Wegovy^®): A BMI of 30 or above, or a BMI of 27 or above with at least one health problem related to weight

2. To manage diabetes (Ozempic^®, SubMagna™, and Rybelsus^®): A diagnosis of type 2 diabetes

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Individuals should talk to their doctor to find out if they can take semaglutide and if it's right for their health goals.

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Compounding Pharmacies

Compounding pharmacies are regulated entities that customize medications for individual patient needs ^[8]. These pharmacies source their ingredients from FDA-registered facilities, often using the same suppliers as drug manufacturers ^[9]. Compounding pharmacists follow specific processes to create medications, including semaglutide, based on approved drug formulations ^[8].

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To ensure safety and legitimacy when using a compounding pharmacy:

1. Verify the pharmacy's state license using FDA-provided resources ^[9].

2. Request independent lab testing results for safety, sterility, and quality ^[8].

3. Ensure the pharmacy requires a prescription specifically for compounded semaglutide ^[8].

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Online Providers

With the increasing demand for weight-loss medications, numerous online companies have emerged, offering telehealth prescribing of compounded versions ^[9]. These providers may offer convenience and lower prices. When considering online providers:

1. Use the National Association of Boards of Pharmacy's search tool to verify legitimacy ^[9].

2. Be wary of sites promising 24-hour delivery or unusually low prices ^[8].

3. Consult the FDA's BeSafeRx resource before purchasing from online pharmacies ^[8].

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Getting semaglutide from a reputable source like TryEden.com has many benefits. You start with an easy online consultation with a healthcare provider, then get a semaglutide plan prescribed that’s tailored just for you. Eden connects you with doctors who ensure you get expert advice and a treatment plan that personally fits you.

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It's crucial to note that some online retailers may lack proper licenses or oversight ^[8]. Legitimate providers will always require a prescription and should not advertise compounded versions using brand names like "Ozempic^®" or "Wegovy^®" ^[9].

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How to Choose a Reputable Compounding Pharmacy for Semaglutide

Selecting a trustworthy compounding pharmacy is crucial for obtaining safe and effective compounded semaglutide. Here are key factors to consider:

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1. Verify Licensing and Accreditation:
   Ensure the pharmacy is properly licensed in your state. Check your state's Board of Pharmacy website to confirm the pharmacy's license status and disciplinary record ^[10]. Look for accreditations from reputable organizations like the Pharmacy Compounding Accreditation Board (PCAB) or the National Association of Boards of Pharmacy. These accreditations indicate compliance with national standards for compounded medications.

2. Check for FDA Registration:
   Compounding pharmacies should source ingredients from FDA-registered facilities ^[9]. Ask the pharmacist about their ingredient sources and verify the registration status using the FDA's online database.

3. Require a Prescription:
   Legitimate compounding pharmacies always require a valid prescription for semaglutide. Be wary of any pharmacy offering to sell semaglutide without a prescription, as this may indicate a counterfeit product.

4. Avoid Misleading Marketing:
   Be cautious of pharmacies advertising compounded semaglutide as "generic" versions of brand-name medications like Ozempic^® or Wegovy^®. Compounded medications are not FDA-approved generics and should not be marketed as such.

5. Consult with a Licensed Pharmacist:
   A reputable pharmacy should have a licensed pharmacist available to answer questions about the medication, its proper use, and potential side effects.
6. Use Verified Online Resources:
   Utilize the FDA's BeSafeRx program and the National Association of Boards of Pharmacy's search tool to verify the legitimacy of online pharmacies ^[10]. People can also perform a web search using the term “semaglutide injections near me” to find physical pharmacies in their local area.

By following these guidelines, individuals can increase their chances of finding a reputable compounding pharmacy for semaglutide, ensuring both safety and quality in their weight management journey.

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The Process of Obtaining Compounded Semaglutide

Step #1: Consult with a Healthcare Provider

The first step in obtaining compounded semaglutide is to consult with a healthcare provider who specializes in diabetes management or weight loss. During this consultation, the provider will evaluate the patient's overall health, review their medical history, and determine if compounded semaglutide is an appropriate treatment option ^[11]. Patients must be open and honest about their health concerns and any current medications they're taking.

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Step #2: Obtain a Prescription

If the healthcare provider determines that compounded semaglutide is suitable, they will provide a prescription. It's important to note that compounded semaglutide always requires a valid prescription from a licensed healthcare professional. Patients should be cautious of any pharmacy or website offering to sell semaglutide without a prescription, as this may indicate a counterfeit product.

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Step #3: Find a Reputable Compounding Pharmacy

Locating a trustworthy compounding pharmacy is crucial. Patients can start by asking their healthcare provider for recommendations or conducting online research. When selecting a pharmacy, it's important to verify that it's properly licensed in the state and accredited by organizations such as the National Association of Boards of Pharmacy or the Pharmacy Compounding Accreditation Board. Patients can use the FDA's online resources to check a pharmacy's licensing status.

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Step #4: Fill the Prescription

Once a reputable compounding pharmacy has been chosen, patients can have their prescriptions filled. The pharmacist will prepare the medication according to the healthcare provider's instructions. Compounded semaglutide may be available in various forms, including injections, sublingual drops, or oral tablets. Patients should discuss with their pharmacist the proper storage, handling, and administration of the medication to ensure its effectiveness and safety. 

If patients don't have insurance coverage, they have an available option through Eden when it comes to how to get semaglutide without insurance. The semaglutide injection price offered by Eden is $296 per month, which is a low-cost option to get semaglutide without insurance. This price remains consistent across all dosage levels and doesn't require insurance. Eden provides compounded semaglutide that is designed to be administered weekly as a self-injection, and also offers a discount for the first month, bringing the price down to $196.

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Compounded Semaglutide vs Other Semaglutide Formulations

Compounded semaglutide and FDA-approved semaglutide formulations, such as Ozempic^®, Wegovy^®, SubMagna™, and Rybelsus^®, share the same active ingredient but differ significantly in their development, approval process, and potential uses. While compounded semaglutide is custom-made by specialized pharmacies, FDA-approved versions undergo rigorous testing and review to ensure safety and efficacy for their intended uses.

One key distinction is that compounded semaglutide is not FDA-approved, and its safety and effectiveness have not been established to the same degree as commercial products. This means that the results obtained from compounded semaglutide may not be equivalent to those of FDA-approved medications.

Compounded semaglutide may be available in various forms, including injections, sublingual drops, orally disintegrating tablets (ODTs), and nasal sprays. The absorption rates and effectiveness of these alternative dosage forms have not been thoroughly studied in humans. It's important to note that compounded semaglutide is not a generic version of Ozempic^® or Wegovy^®. There are currently no FDA-approved generic versions of these medications. Compounded semaglutide may contain additional ingredients that haven't been tested with semaglutide, such as vitamin B12 or BPC-157.

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Final Thoughts on How to Get Compounded Semaglutide

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Obtaining compounded semaglutide for weight management involves a careful process that starts with consulting a healthcare provider and ends with filling a prescription at a reputable compounding pharmacy. This journey requires thorough research and attention to safety, as compounded medications aren't FDA-approved and may differ from their brand-name counterparts. It's important to work closely with healthcare professionals to ensure the medication is appropriate for individual needs and to monitor its effectiveness.

While compounded semaglutide offers potential benefits for weight loss and blood sugar control, it's essential to approach its use with caution and realistic expectations. By understanding the differences between compounded and FDA-approved formulations, patients can make informed decisions about their treatment options. As the landscape of weight management continues to evolve, staying informed and maintaining open communication with healthcare providers remain key to achieving safe and effective results.

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How to Get Compounded Semaglutide FAQ

1. Is compound semaglutide as effective as FDA-approved semaglutide formulations?

Compounded semaglutide and FDA-approved formulations like Ozempic^® and Wegovy contain the same active ingredient: semaglutide. There are significant differences in their development, approval process, and potential effectiveness ^[1].

The FDA has not assessed the effectiveness of compounded semaglutide, so it's unknown if it's as effective as FDA-approved products ^[1]. Compounded medications don't undergo the same testing and review process as FDA-approved drugs, which means their safety and efficacy haven't been established to the same degree.

It's important to note that compounded semaglutide is not a generic version of Ozempic^® or Wegovy^®, as there are currently no FDA-approved generic versions of these medications ^[13].

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2. How does compounded semaglutide work for weight loss?

Semaglutide, whether compounded or FDA-approved, belongs to a class of drugs called GLP-1 receptor agonists. It mimics the action of the GLP-1 hormone, which plays a role in regulating blood sugar levels and appetite ^[14].

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The medication works by:

1. Slowing down gastric emptying, making you feel full for longer

2. Reducing appetite by acting on the brain's appetite centers

3. Promoting the release of insulin when blood sugar levels rise

These combined effects can lead to reduced food intake and subsequent weight loss ^[14].

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3. What are the potential risks of using compounded semaglutide?

While compounded semaglutide may offer an alternative during shortages of FDA-approved products, it comes with potential risks:

1. Unknown safety and effectiveness due to lack of FDA evaluation

2. Possible use of inappropriate ingredients or unknown impurities ^[15]

3. Risk of contamination, especially with injections ^[15]

4. Potential dosing errors due to lack of safety features in compounded vials ^[15]

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The FDA has raised concerns about salt-compounded forms of semaglutide, stating that these versions may not be safe or effective ^[16].

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4. How can I obtain compounded semaglutide safely?

To obtain compounded semaglutide as safely as possible:

1. Consult a qualified healthcare professional for a prescription and guidance ^[3]

2. Choose a reputable, licensed compounding pharmacy ^[9]

3. Verify that the pharmacy sources ingredients from FDA-registered facilities ^[9]

4. Be cautious of online pharmacies advertising "compounded Ozempic^®" or similar products ^[9]

5. Discuss potential risks and benefits with your healthcare provider ^[3]

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Remember, while compounded medications can serve an important purpose, they should be approached with caution and under proper medical supervision.

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Disclaimer: The FDA does not approve compounded medications for safety, quality, or manufacturing. Prescriptions and a medical evaluation are required for certain products. The information provided on this blog is for general informational purposes only. It is not intended as a substitute for professional advice from a qualified healthcare professional and should not be relied upon as personal health advice. The information contained in this blog is not meant to diagnose, treat, cure, or prevent any disease. Readers are advised to consult with a qualified healthcare professional for any medical concerns, including side effects. Use of this blog's information is at your own risk. The blog owner is not responsible for any adverse effects or consequences resulting from the use of any suggestions or information provided in this blog.

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References

1. RedBox Rx Editorial Team, Fick, MD D. Compounded Semaglutide: Complete Guide. Redboxrx.com. Published September 6, 2024. Accessed September 10, 2024. https://www.redboxrx.com/blog/compounded-semaglutide-everything-you-need-to-know

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2. Mayo Clinic. Semaglutide (Subcutaneous Route) Proper Use. www.mayoclinic.org. Published 2024. Accessed September 10, 2024. https://www.mayoclinic.org/drugs-supplements/semaglutide-subcutaneous-route/proper-use/drg-20406730

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3. Billingsley A, Woodcock S. Is Compounded Semaglutide Safe? Here’s What You Should Know. GoodRx. Published August 1, 2024. Accessed September 10, 2024. https://www.goodrx.com/classes/glp-1-agonists/compounded-semaglutide

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4. Rejuvime Medical. How Fast Does Semaglutide Work for Weight Loss? Rejuvime Medical. Published August 11, 2023. Accessed September 10, 2024. https://www.rejuvimemedical.com/blog/how-fast-does-semaglutide-work-for-weight-loss/

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5. Garland J. The Ultimate Guide to Compounded Semaglutide Shots for Weight Loss. ColoradoBeautyRN. Published September 25, 2023. Accessed September 10, 2024. https://coloradobeautyrn.com/blogs/news/the-comprehensive-guide-to-compounded-semaglutide-shots-for-weight-loss

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6. Vive Ageless Weight Loss Center. Compounded Semaglutide vs. Ozempic, WeGovy, and Mounjaro. ViveAgelessWeightLoss.com. Published 2024. Accessed September 10, 2024. https://www.viveagelessweightloss.com/compounded-semaglutide

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7. Taylor, MD, Southwest Family Medical. The Pros and Cons of Semaglutide for Weight Loss. Southwest Family Medical. Published September 7, 2023. Accessed September 10, 2024. https://swfamilymedical.com/pros-cons-semaglutide-for-weight-loss/

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8. Park A. Are Compounded Versions of Popular Weight Loss Drugs Safe? TIME. Published November 20, 2023. Accessed September 10, 2024. https://time.com/6301552/weight-loss-drugs-compounding-pharmacies/

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9. Lupkin S. Thinking of buying Wegovy online. Here’s what to know about compounding pharmacies. NPR. Published June 7, 2024. Accessed September 10, 2024. https://www.npr.org/sections/shots-health-news/2024/06/07/g-s1-3331/wegovy-online-compound-semaglutide-compounding-pharmacies

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10. Brown S. Compounded Semaglutide — What Is It And Where To Get It? Klarity Health, Inc. Published May 13, 2024. Accessed September 10, 2024. https://www.helloklarity.com/post/compounded-semaglutide/

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11. Contigo Compounding Pharmacy and Infusion Therapy. Navigating the Compounded Semaglutide Prescription Process. Contigocompounding.com. Published April 1, 2024. Accessed September 10, 2024. https://contigocompounding.com/2024/04/01/navigating-the-compounded-semaglutide-prescription-process/

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12. Sissons B. Is Compounded Semaglutide the Same as Ozempic? Healthline. Published June 7, 2024. Accessed September 10, 2024. https://www.healthline.com/health/drugs/compounded-semaglutide-vs-ozempic

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13. Kansas State Board of Pharmacy. Statement on Compounding and Dispensing of Compounded Semaglutide and Other GLP-1 Receptor Agonists.; 2024. Accessed September 10, 2024. https://pharmacy.ks.gov/docs/librariesprovider10/guidance-documents/guidance-on-compounding-semaglutide.pdf?sfvrsn=5dff00d1_0

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14. Richland B. Semaglutide Weight Loss Comprehensive Guide for Beginners. Dr. Brandon Richland, MD. Published September 7, 2023. Accessed September 10, 2024. https://www.richlandmd.com/cosmetic/semaglutide-weight-loss/

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15. Cain G. Semaglutide: How to Inject. Prestons Pharmacy. Published August 30, 2023. Accessed September 10, 2024. https://prestonspharmacy.com/semaglutide-how-to-inject/

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16. Gillette H. What Are the Best Foods to Eat When Prescribed Semaglutide? Healthline. Published April 4, 2024. Accessed September 10, 2024. https://www.healthline.com/health/diet-and-weight-loss/semaglutide-food-list