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Starting on Sermorelin

By The TryEden Team
By The TryEden Team
September 12, 2024
|
9 minute read
Starting on Wegovy

We're beyond excited you're here!

We're excited that you've chosen to explore Sermorelin as part of your wellness journey! This guide will provide you with important information on how to integrate Sermorelin into your routine. Whether you’re looking to support your overall wellness, maintain your energy, or explore its potential benefits, we’re here to guide you every step of the way.

In this guide, we will explore:

  1. How to integrate Sermorelin into your routine.
  2. The step-by-step process for Sermorelin administration and dosage.
  3. Answers to frequently asked questions.
  4. Important safety information.

Welcome To The Program!

We’re glad you’ve chosen Sermorelin as part of your wellness journey! At Eden, our mission is to support you with the resources and guidance you need to explore this treatment. Whether your goals include maintaining your energy, supporting muscle function, or focusing on general wellness, Sermorelin can be a valuable tool in your plan. Together, we’ll ensure you have the support you need throughout your journey.

How Sermorelin Can Support Your Wellness Goals

Mechanism of Action: Sermorelin is a synthetic analog of growth hormone-releasing hormone (GHRH). It stimulates the pituitary gland to naturally increase the production and release of growth hormone. This mechanism may support your wellness goals by contributing to various physiological processes, such as:

  • Muscle Growth and Recovery: Sermorelin may promote muscle protein synthesis, which can help improve muscle growth and enhance recovery times after exercise. This can be particularly beneficial for individuals looking to optimize their muscle health and physical performance. [1]
  • Body Composition and Weight Management: By stimulating growth hormone production, Sermorelin may aid in lipolysis, the process of breaking down fats, which can help reduce body fat and preserve lean muscle mass. This may contribute to improved body composition. [2]
  • Cardiovascular Health: Growth hormone plays a critical role in maintaining cardiovascular function by enhancing heart muscle strength, blood vessel elasticity, and reducing levels of harmful low-density lipoprotein (LDL) cholesterol. Sermorelin’s stimulation of natural growth hormone may lead to improved cardiovascular health. [3]

Note: These statements are based on the general understanding of Sermorelin's mechanism of action and do not imply specific health outcomes. Always consult your healthcare provider for personalized advice.

What Should My Journey Look Like?

Your journey with Sermorelin is designed to be simple and effective, fitting seamlessly into your daily routine. Here’s what to expect:

Follow the Suggested Dosage Set by your Medical Provider. A suggested starting dosage may be:

  • Administer 0.1-0.2ml (10-20 syringe units) subcutaneously, 5-7 days per week, preferably before bedtime. This timing aligns with your body’s natural growth hormone release.

What to Expect in the First Few Weeks

  • Initial Reactions: You may start noticing increased energy and improved recovery times within the first few weeks. Some mild side effects like slight redness at the injection site or minor dizziness may occur, but these typically resolve as your body adjusts.

Continuing with Your Program

  • Ongoing Dosage: Maintain your regular dosing schedule as advised by your healthcare provider. A 5ml Sermorelin vial will be shipped to you every month for 6 months or until your plan is modified.
  • Sustained Results: Over time, you may experience continued improvements in muscle tone, fat loss, and energy levels. Consistency is key, so stick with your routine and keep your healthcare provider informed of your progress.

Maximizing Your Results

  • Sermorelin works best when combined with a healthy lifestyle. This means focusing on balanced nutrition, regular exercise, and other positive habits that support your wellness goals.

FAQ

Q: How do I give myself the Sermorelin injection?

Don’t worry—it’s easier than you might think! Here’s a quick guide:

Self-Administration: A Simplified Process

  • Wash Your Hands: Clean your hands thoroughly with soap and warm water for at least 20 seconds.
  • Get Your Injection Supplies Ready:
    • Needle and syringe with medication, or an auto-injector pen.
    • Alcohol pads.
    • Gauze.
    • A sharps container for needle disposal.
    • Bandages (if needed)
  • Prepare the Injection Site: Check the area of skin where you'll inject for any issues. Choose a different site each time to prevent skin problems. Clean the area with an alcohol pad and let it dry.
    The most common injection sites are:
    • Abdomen: at or below belly button level, about two inches away from the navel. 
    • Arm: back or side of the upper arm
    • Thigh: front of the thigh
  • Prepare the Medication Syringe:
    • Wipe the top of the medication vial with an alcohol pad.
    • Draw air into the syringe equal to your medication dose.
    • Push the needle through the vial's rubber stopper, inject the air, and turn the vial upside down.
    • Draw your medication dose into the syringe.
    • Tap any air bubbles and push them out of the syringe.
  • Giving the Injection:
    • Pinch an inch of skin between your thumb and forefinger.
    • Quickly insert the needle all the way into the pinched skin at a 90-degree angle (or 45 degrees if you have less body fat).
    • Push the plunger slowly until you've injected all the medication.
    • Release the pinch and carefully pull out the needle.
    • Dispose needle and syringe into sharps container.
  • After the Injection:
    • If there's a bit of bleeding, press lightly with gauze.
    • Cover with a bandage if needed.
  • Important Tips:
    • Rotate your injection sites to avoid discomfort and skin issues.
    • If you notice severe pain, redness, swelling, warmth, or drainage at the injection site, contact your doctor immediately as these could be signs of an infection.

Q: What if I miss a dose?

  • Answer: If you forget to take a dose, administer it as soon as you remember, unless it’s close to your next scheduled dose. In that case, skip the missed dose—never double up. If you’re unsure, reach out to your healthcare provider.

Q: Are there any side effects I should be aware of?

  • Answer: Common side effects include redness, swelling at the injection site, and dizziness. These are generally mild and temporary. Rare side effects may include itching, trouble swallowing, or changes in blood pressure. Serious side effects are rare but may include severe allergic reactions. Seek medical help immediately if you experience any severe symptoms.

Q: Can Sermorelin interact with other medications?

  • Answer: Yes, Sermorelin can interact with medications like glucocorticoids and thyroid hormones, which can affect growth hormone levels. Always inform your healthcare provider of all medications you are taking.

Q: Who should not use Sermorelin?

  • Answer: Individuals with a known allergy to Sermorelin or any of its components, pregnant or breastfeeding women, and those with active cancer should not use Sermorelin. Additionally, patients with underactive thyroid (hypothyroidism) should use caution as this condition can interfere with the effects of Sermorelin. [5]

Q: What are the long-term complications associated with Sermorelin injection?

  • Answer: Long-term use of Sermorelin injections may lead to complications such as persistent injection site reactions, carpal tunnel syndrome, fluid retention (edema), insulin resistance, and potentially an increased risk of cancer due to sustained growth hormone stimulation.[3]

Q: What is Growth Hormone (GH) Cycling and why is it important?

  • Answer: GH cycling involves the intermittent use of Sermorelin to stimulate natural growth hormone production, followed by periods of discontinuation. This method helps prevent desensitization of the pituitary gland's receptors, reduces the risk of long-term side effects, and mimics natural hormone release patterns. [6]

Q: What is the best way to discontinue Sermorelin?

  • Answer: Discontinuing Sermorelin should be done cautiously and under the supervision of a healthcare provider. The recommended steps include:
    1. Consult Your Healthcare Provider: Before making any changes to your sermorelin regimen, it's crucial to consult with your healthcare provider. They can provide personalized advice based on your medical history and current health status.
    2. Gradual Tapering: Instead of stopping abruptly, it may be beneficial to gradually reduce the dosage of sermorelin over a period. This helps the body adjust to the decreasing levels of the hormone and minimizes potential withdrawal effects.
    3. Monitor for Withdrawal Symptoms: During the tapering process, monitor for any adverse symptoms such as fatigue, muscle weakness, or mood changes. If severe symptoms occur, contact your healthcare provider immediately.
    4. Supportive Care: Maintain a healthy lifestyle with a balanced diet, regular exercise, and adequate sleep to support your body during the discontinuation process.
      Consider supplements or other therapies as recommended by your healthcare provider to support overall health and well-being. [7]


Ongoing Support and Resources

Your health journey is important to us, and we’re here to support you every step of the way. Whether you have questions about your treatment, need assistance with administration, or just want to check in, you can always reach out through your HIPAA-secure Eden Portal. Our team is ready to assist you with any concerns or questions you might have.

Important Safety Information and Common Side Effects

Safety Information Contraindications Hypersensitivity to Sermorelin or any of its ingredients, pregnancy, breastfeeding, and active cancer. Mayo Clinic Sermorelin Precautions monitoring of growth hormone levels, blood sugars levels, and overall health by a healthcare provider.

Common: Pain, redness, or selling at the place of injection

Rare: Itching, trouble swallowing, dizziness, flushing, headache, sleepiness, trouble sitting still

Disclaimer: The statements above have not been reviewed by the Food and Drug Administration. This product is not designed to diagnose, treat, cure, or prevent any condition.

Who Shouldn’t Use Sermorelin:

  • Individuals allergic to any of the ingredients, pregnant or breastfeeding women, and those with active cancer should not use Sermorelin. Always consult your healthcare provider to ensure this treatment is right for you.

Precautions:

  • Regular monitoring of growth hormone levels, blood sugar, and overall health is recommended while using Sermorelin.

Storage Instructions:

  • Store Sermorelin in the refrigerator (2-8°C / 36-46°F). Do not freeze and protect from light. Follow the beyond-use date provided by your pharmacy. Discard vial 28 days after initial puncture.


This is for general information only and not intended to be medical advice. Eden does not practice medicine or prescribe. Consult with your healthcare professional for more information. FDA does not approve compounded medication for safety or quality. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

What To Expect When You Are Expecting
(A Delivery From Us).

At Eden, we prioritize a systematic approach towards achieving your health goals. Since you've made the decision to place your trust in us on this journey, we wanted to inform you of what's next.
Our streamlined process ensures a seamless transition towards better health, all from the comfort of your home.

Stage 1:

Prescription Approval:
  • Since you recently completed your initial intake consultation order with our healthcare professionals, they will begin the process to review your health-history in detail. They may have questions for you, so be on the lookout for any messages from your doctor. You can access your secure, HIPAA-compliant, patient portal at any time to respond back to the doctor.
  • This process typically takes ~1-2 days
Prescription Approval:

Stage 2:

Pharmacy Processing
  • If a physician deems treatment as appropriate, you may receive a tailored health plan with medication suited to your unique health narrative.
  • This will release your prescription to an accredited pharmacy to prepare your medication.
  • This will release your prescription to an accredited 503A compounding pharmacy to personalize the medication just for you.
  • This process typically takes ~3-5 business days. Sometimes slight delays can occur - we value delivering quality, and sometimes quality takes time!
Pharmacy Processing

Stage 3:

Shipping
  • Once your prescription is ready to ship, you’ll receive a notification from us with the tracking information. Our partners ship FedEx or UPS, and you may receive your package Monday to Saturday.
  • This process typically takes ~2 days
Shipping

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Citations:

1. Walker R. F. et al. (1990). "Sermorelin: a growth hormone releasing hormone analog." Journal of Clinical Endocrinology & Metabolism. Link

2. Holloway L. et al. (1994). "The effects of growth hormone releasing hormone on body composition and metabolism in adults." Clinical Endocrinology. Link

3. Savine R. et al. (1999). "Growth hormone replacement therapy and cardiovascular health in adults." Endocrine Reviews. Link

4. Khorram O. et al. (2001). "The effect of GHRH on body composition and muscle strength in aging men." Journal of Endocrinological Investigation. Link

5. Mayo Clinic. (n.d.). Sermorelin (injection route) side effects. Link

6. Veldhuis J. D. et al. (1992). "Growth hormone secretory responses to GHRH in bodybuilders." Journal of Applied Physiology. Link.

7. Salomon F. et al. (1989). "Growth hormone release in humans." Journal of Clinical Endocrinology & Metabolism. Link